Which of the following is NOT a finding within 24 hrs of starvation in a 19-year-old patient with Anorexia Nervosa?
**Core Concept**
Starvation, particularly in the context of Anorexia Nervosa, leads to significant physiological changes. Within 24 hours, the body begins to adapt to conserve energy, mobilize stored glucose, and switch to alternative energy sources.
**Why the Correct Answer is Right**
The correct answer will be the option that does not occur within 24 hours of starvation in a patient with Anorexia Nervosa. Typically, within this timeframe, the body starts to break down stored glycogen, releasing glucose into the bloodstream. This process is mediated by the enzyme glycogen phosphorylase, which cleaves glycogen into glucose-1-phosphate. The liver also begins to produce ketone bodies as an alternative energy source, utilizing fatty acids that are released from adipose tissue. Additionally, the body starts to conserve insulin and glucagon levels, with a slight increase in glucagon to promote glycogenolysis and gluconeogenesis.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because the body starts to break down stored glycogen and release glucose into the bloodstream within 24 hours of starvation.
* **Option B:** This option is incorrect because the liver begins to produce ketone bodies as an alternative energy source within 24 hours of starvation.
* **Option C:** This option is incorrect because the body starts to conserve insulin and glucagon levels, with a slight increase in glucagon to promote glycogenolysis and gluconeogenesis, within 24 hours of starvation.
**Clinical Pearl / High-Yield Fact**
It is essential to recognize the physiological changes that occur within 24 hours of starvation in patients with Anorexia Nervosa, as these changes can impact treatment decisions and management strategies.
**Correct Answer:** D