Unknown SS-A (Ro) and SS-B (LA) antibodies found in Sjogren syndrome are targeted against: A DNA topoisomerase 1 B Histones C Ribonucleoproteins D Native DNA 💡 Explanation SS-A (Ro) and SS-B (LA) antibodies found in Sjogren syndrome are targeted against: ✓ Correct Answer: C. Ribonucleoproteins