Treatment of choice for sputum positive pulmonary tuberculosis detected in 1st trimester of pregnancy?
**Core Concept**
The treatment of pulmonary tuberculosis (TB) during pregnancy involves considering the risks and benefits of various antitubercular drugs to both the mother and the fetus. **Pregnancy** complicates TB treatment due to potential teratogenic effects of some drugs.
**Why the Correct Answer is Right**
The standard treatment regimen for TB typically includes a combination of **isoniazid**, **rifampicin**, **ethambutol**, and **pyrazinamide**. However, during pregnancy, especially in the first trimester, it's crucial to balance efficacy with fetal safety.
**Why Each Wrong Option is Incorrect**
**Option A:** Incorrect due to lack of specification.
**Option B:** Not the first-line choice.
**Option D:** Not typically used as initial therapy.
**Clinical Pearl / High-Yield Fact**
It's crucial to initiate treatment as soon as possible to prevent maternal and fetal complications, and the regimen should be tailored based on drug susceptibility patterns when available.
**Correct Answer:** D. Standard antitubercular therapy with careful monitoring.