Speed of onset of action of local anaesthetics is indicated by –
Correct Answer: Blood : gas paition coefficient
Description: Ans. is 'b' i.e., Blood : gas paition coefficient Minimal alveolar concentration It is the lowest concentration of the anaesthetic in pulmonary alveoli needed to produce immobility in response to a painful stimulus (surgical incision) in 50% individuals. It is the measure of potency of inhalation GAs. Blood : gas paition cofficient It is the measure of solubility of agent in blood. It determines the speed of onset and recovery. Higher the blood : gas paition cofficient, lesser the speed of induction and recovary --> more blood soluble agents have slower induction and recovery. Oil : gas paition cofficient It is the measure of lipid solubility of the agent, and therefore solubility in the fat - rich tissues of the CNS. This equates with the potency of individual agents. There is a direct relationship between the minimum alveolar concentration (MAC) value of inhaled anaesthetic agents and lipid solubility in terms of the oil/gas paition cofficient.
Category:
Anaesthesia
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now