Microbiology Specific immunological unresponsiveness is called tolerance. Which one of the following statements best describes immunological tolerance? A Immunologic maturity of the host does not play a major role B It occurs only with polysaccharide antigens C It is related to the concentration of antibody D It is prolonged by administration of immunosuppressive drugs 💡 Explanation Specific immunological unresponsiveness is called tolerance. Which one of the following statements best describes immunological tolerance? ✓ Correct Answer: D. It is prolonged by administration of immunosuppressive drugs