Forensic Medicine Softening of uterine isthmus and lower segment in early pregnancy is known as: UP 07; MAHE 11 A Hegar's sign B Braxton Hick's sign C Goodell's sign D Osiander's sign 💡 Explanation Softening of uterine isthmus and lower segment in early pregnancy is known as: UP 07; MAHE 11 ✓ Correct Answer: A. Hegar's sign