**Core Concept**
The question refers to the eradication of Smallpox, a contagious and sometimes fatal infectious disease caused by the variola virus. The global effort to eradicate Smallpox was led by the World Health Organization (WHO) and involved the development of a vaccine, surveillance, and containment strategies.

**Why the Correct Answer is Right**
The last naturally occurring case of Smallpox was reported in Somalia in 1977. The disease was eradicated through a concerted global effort, which included the development of a highly effective vaccine by Edward Jenner in 1796. The vaccine was administered to millions of people worldwide, and the disease was eventually eliminated from the environment. The success of the Smallpox eradication program is considered one of the greatest achievements in the history of public health.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not specify a location or year, making it an ambiguous choice.
**Option B:** This option is incorrect because it does not accurately represent the location of the last naturally occurring case of Smallpox.
**Option C:** This option is incorrect because it is not supported by scientific evidence, and there is no record of Smallpox occurring in this location.

**Clinical Pearl / High-Yield Fact**
The eradication of Smallpox serves as a model for global health initiatives and highlights the importance of vaccination, surveillance, and containment strategies in preventing the spread of infectious diseases.

**Correct Answer: D. Somalia, 1977**