Single best prognostic indicator of successful treatment with single-dose Methotrexate is
Correct Answer: Serum b-hCG level
Description: The best candidate for medical therapy is the woman who is asymptomatic, motivated, and compliant. With medical therapy, some classic predictors of success include a low initial serum b-hCG level, small ectopic pregnancy size, and absent fetal cardiac activity. Of these, initial serum b-hCG level is the single best prognostic indicator of successful treatment with single-dose MTX. Specifically, repoed failure rates are 1.5 percent if the initial serum b-hCG concentration is <1000 mIU/mLReference: William's Obstetrics; 25th edition; Chapter 19; Ectopic pregnancy
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Gynaecology & Obstetrics
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