Side effect of cisplatin include all the following except
**Core Concept**
Cisplatin is a **chemotherapeutic agent** used to treat various types of cancer, including testicular, ovarian, lung, bladder, and stomach cancers. Its mechanism of action involves forming **platinum-DNA adducts** that interfere with DNA repair, leading to cell death. Cisplatin's side effects are largely due to its **nephrotoxicity**, **neurotoxicity**, and **ototoxicity**.
**Why the Correct Answer is Right**
The correct answer choice is not provided, so let's discuss the common side effects of cisplatin. Cisplatin can cause **nephrotoxicity**, leading to acute kidney injury, **neurotoxicity**, resulting in peripheral neuropathy, and **ototoxicity**, causing hearing loss. It can also induce **nausea and vomiting**, **myelosuppression**, and **hypomagnesemia**.
**Why Each Wrong Option is Incorrect**
**Option A:** Without the specific option, it's challenging to provide a detailed explanation.
**Option B:** Similarly, without the option, it's difficult to explain why it's incorrect.
**Option C:** And again, the lack of a specific option makes it hard to provide a reason.
**Option D:** The same issue applies here.
**Clinical Pearl / High-Yield Fact**
A crucial point to remember is that **hydration** and **diuresis** are essential to minimize cisplatin's **nephrotoxicity**.
**Correct Answer:** Unfortunately, the answer choices are not provided.