Sickle cell disease is present with which mutation:

Correct Answer: Base pair substitution
Description: Ans. (d) Base pair substitutionRef: Harper's Biochemistry, 30th ed. pg. 416-17A partial missense mutation (type of base pair substitution) glutamic acid, the normal amino acid in position 6 of the b chain, has been replaced by valine.
Category: Biochemistry
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