Sickle cell disease associated with which type of renal cell carcinoma?
Correct Answer: Medullary
Description: A i.e. MedullaryRef: WHO, Urogential System, page 122Explanation:Medullary Renal Cell CarcinomaRare, highly aggressive medulla centered carcinoma.Associated with sickle cell trait* or other hemoglobinopathies*.Rare carcinoma arising in the renal medulla.Occurs predominately in young patients with sickle cell trait.Variety of histologic patterns.Sickied erythrocytes may be pathognomonic.Majority show loss of SMARCB1 /INI1*.Poor prognosis*.
Category:
Pathology
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