Medical MCQ-Sickle cell anemia is the clinical manifestation of homozygous genes for an abnormal haemoglobin molecule. The event responsible for the mutation in the b chain is:

Sickle cell anemia is the clinical manifestation of homozygous genes for an abnormal haemoglobin molecule. The event responsible for the mutation in the b chain is:

Inseion

Deletion

Non-disjunction

Point mutation

Question Category:

Pathology

Correct Answer:

Point mutation

Description:

- Sickle cell disease is a common hereditary hemoglobinopathy caused by point mutation resulting in replacement of Glutamic acid by Valine at 6th position of b-globin chain.

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