Which of the following features is not shared between ‘T cells’ and B cells’?
**Core Concept**
T cells and B cells are both lymphocytes that play a crucial role in the adaptive immune response. They share many characteristics, but there are distinct differences between the two.
**Why the Correct Answer is Right**
T cells and B cells both undergo clonal expansion and differentiation in response to antigen recognition. They also express cell surface receptors that recognize specific antigens, such as the T cell receptor (TCR) on T cells and the B cell receptor (BCR) on B cells. However, the main difference lies in their function and mechanism of action. T cells primarily mediate cell-mediated immunity, while B cells produce antibodies to neutralize pathogens.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because T cells and B cells both undergo clonal expansion in response to antigen recognition.
* **Option B:** This option is incorrect because T cells and B cells both express cell surface receptors that recognize specific antigens.
* **Option C:** This option is incorrect because T cells and B cells both play a crucial role in the adaptive immune response.
* **Option D:** This option is incorrect because T cells and B cells both undergo differentiation in response to antigen recognition.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that T cells and B cells have distinct functions and mechanisms of action, which is crucial for understanding immune dysregulation and autoimmune diseases.
**Correct Answer:** D.