Shape of RBC is biconcave due to?

Correct Answer: Spectrin
Description: The most impoant constituent of the cytoskeleton is protein spectrin. Includes alpha and beta chains.Interwined spectrin molecules are linked together by other cytoskeletal proteins and actin to form a lattice like network which is attached to the internal surface of the membrane.This network is a resilent structure which normally causes red cells to resume the biconcave disc form after forces causing distoion are removed Ref:deGruchy's clinical haematology in medical practice 6th adapted edition.page no.16 Ref Robbins 9/e pg 410
Category: Pathology
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