True about Sevoflurane – a) Isopropyl etherb) MAC is 2%c) Good to use in old aged) Blood gas partition coefficient is more than halothanee) Formation of compound A with baralyme
**Question:** True about Sevoflurane - a) Isopropyl ether, b) MAC is 2%, c) Good to use in old aged, d) Blood gas partition coefficient is more than halothane, e) Formation of compound A with baralyme
**Core Concept:** Sevoflurane is a volatile anesthetic agent used for general anesthesia induction and maintenance. It is a member of the fluorinated ether group of anesthetic agents. MAC (Minimum Alveolar Concentration) is a measure of the concentration of anesthetic required to suppress electromyographic activity in 50% of patients. Blood gas partition coefficient is a measure of how well a substance distributes between the blood and the surrounding tissue.
**Why the Correct Answer is Right:**
a) Isopropyl ether (also known as Isovaler ether) is a different type of anesthetic agent, not a part of the fluorinated ether group. Sevoflurane belongs to the fluorinated ether group.
b) MAC refers to the concentration of anesthetic required to suppress electromyographic activity in 50% of patients. MAC values vary between individuals and are not a fixed percentage. MAC for sevoflurane is approximately 1.0 to 1.5 for induction and 0.8 to 1.2 for maintenance.
c) The choice "Good to use in old aged" is subjective and not a scientific fact. Sevoflurane's safety profile has been studied across a wide range of patients, including the elderly, and it is considered safe and effective in this population.
d) The blood gas partition coefficient of sevoflurane (2.02) is slightly higher than that of halothane (1.55), making sevoflurane better distributed in the body, which is beneficial for maintaining anesthesia.
e) Sevoflurane does not form compound A with bromocresol purple (baralyme), while halothane does. This is related to the chemical structure of sevoflurane, which lacks the functional group responsible for compound A formation.
**Why Each Wrong Answer is Incorrect:**
a) Isopropyl ether: As mentioned earlier, isopropyl ether (isoflurane) is a different anesthetic agent and not applicable to sevoflurane.
b) MAC percentage: MAC values are not percentages but concentrations in volumetric terms. They vary between individuals and depend on factors like age, weight, and body composition.
c) Good for old aged: This is not a scientific fact but rather a subjective opinion. Sevoflurane has been demonstrated to be safe and effective in elderly patients.
d) Higher blood gas partition coefficient: Although sevoflurane's blood gas partition coefficient is slightly higher than halothane, this does not directly imply superiority in anesthetic efficacy or safety.
e) Formation of compound A: Sevoflurane does not form compound A with bromocresol purple (baralyme), unlike halothane which does. This difference is due to the absence of the functional group responsible for compound