Pharmacology Several segments of the polypeptide chain of integral membrane proteins usually span the lipid bilayer. These segments frequently (NOT RELATED) A Adopt an a-helical configuration B Contain many hydrophilic amino acids C Form covalent bonds with cholesterol D Contain unusually strong peptide bonds 💡 Explanation Several segments of the polypeptide chain of integral membrane proteins usually span the lipid bilayer. These segments frequently (NOT RELATED) ✓ Correct Answer: A. Adopt an a-helical configuration