TURP was done in an old pt. of BHP, after which he developed altered sensoriuon cause is
**Core Concept**
During a Transurethral Resection of the Prostate (TURP), there is a risk of cerebrospinal fluid (CSF) leakage due to the creation of a communication between the prostate and the subarachnoid space. This can lead to the entry of irrigation fluid, including glycine, into the subarachnoid space, causing a condition known as **glycine syndrome**.
**Why the Correct Answer is Right**
The correct answer is related to the entry of irrigation fluid into the subarachnoid space, causing a condition known as **glycine syndrome**. Glycine is a sugar molecule that can cause cerebral edema and altered mental status when it enters the subarachnoid space. This is because glycine can cause an imbalance in the concentration of ions within neurons, leading to changes in neuronal function and behavior. The entry of glycine into the subarachnoid space can be due to the creation of a communication between the prostate and the subarachnoid space during TURP.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not relate to the entry of irrigation fluid into the subarachnoid space during TURP. While anesthesia can cause altered mental status, it is not directly related to the procedure itself.
**Option B:** This option is incorrect because it is a known complication of TURP, but it is not related to the entry of irrigation fluid into the subarachnoid space. Hypotension is a common complication of TURP due to the absorption of irrigation fluid into the bloodstream.
**Option D:** This option is incorrect because it is a known complication of TURP, but it is not related to the entry of irrigation fluid into the subarachnoid space. Incontinence is a common complication of TURP due to the damage to the urinary sphincter.
**Clinical Pearl / High-Yield Fact**
It is essential to monitor patients closely after TURP for signs of glycine syndrome, including altered mental status, seizures, and coma. Early recognition and treatment of glycine syndrome can prevent serious complications.
**Correct Answer: B. Hypotension**