**Core Concept**
The question requires knowledge of the pharmacological treatment of central diabetes insipidus, specifically the role of V2 receptor agonists in managing this condition. V2 receptors are vasopressin receptors found in the kidneys, which play a crucial role in water reabsorption and maintaining proper fluid balance in the body.
**Why the Correct Answer is Right**
The selective V2 receptor agonist, desmopressin, works by mimicking the action of antidiuretic hormone (ADH) in the kidneys. It binds to V2 receptors, leading to increased water reabsorption and decreased urine production. This results in improved symptoms of central diabetes insipidus, such as polyuria and polydipsia. Desmopressin is a synthetic analogue of vasopressin and is specifically designed to have minimal pressor activity, making it safer for use in patients with diabetes insipidus.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect as there is no commonly used selective V2 receptor agonist by this name.
**Option B:** This option is incorrect as it is not a selective V2 receptor agonist used for treating central diabetes insipidus.
**Option C:** This option is incorrect as it is not a selective V2 receptor agonist used for treating central diabetes insipidus.
**Clinical Pearl / High-Yield Fact**
Desmopressin is a long-acting V2 receptor agonist that can be administered via nasal spray, injection, or orally, making it a convenient option for managing central diabetes insipidus in various patient populations.
**Correct Answer: D. Desmopressin**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.