**Core Concept**
Liver secondaries (metastases) can be treated with various ablation techniques that destroy cancer cells in situ, minimizing the need for surgical resection. Ablation modalities often target the tumor's blood supply or heat-sensitive cellular components.

**Why the Correct Answer is Right**
Radiofrequency ablation (RFA) is a widely used modality for in situ ablation of liver secondaries. It involves the insertion of a probe into the tumor, which emits high-frequency electrical currents to generate heat, coagulating the tumor cells. The heat generated is sufficient to kill cancer cells within a specific radius, while sparing surrounding healthy tissue. Other modalities like microwave ablation (MWA) and cryoablation also work similarly by generating heat or cold to destroy cancer cells.

**Why Each Wrong Option is Incorrect**
**Option A:** Laser-induced interstitial thermotherapy (LITT) is indeed a modality used for ablation of liver secondaries, but it is not the best distractor since it is a viable option.
**Option B:** No option is given for B. Please provide a valid option.
**Option C:** No option is given for C. Please provide a valid option.
**Option D:** No option is given for D. Please provide a valid option.

**Clinical Pearl / High-Yield Fact**
When choosing an ablation modality for liver secondaries, it's essential to consider the size and location of the tumor, as well as the patient's overall health. RFA and MWA are often preferred for smaller tumors, while cryoablation may be used for larger or more complex cases.

**Correct Answer:** A.