**Question:** Features of Deep Second degree burn are:

A. Proliferation of granulation tissue
B. Altered skin sensation
C. Absence of epidermis and dermal papilla
D. Presence of blisters

**Core Concept:**
Deep second-degree burn refers to a burn that extends into the dermal layer, involving both the epidermis and dermis. This type of burn presents with varying clinical features, including skin changes and sensation alterations.

**Why the Correct Answer is Right:**
Deep second-degree burns affect both the epidermis and dermis, leading to the features mentioned in the correct answer:
1. **Presence of blisters:** Blisters are formed due to the rupture of the epidermis and dermal vessels. They are a common feature of burn injuries, particularly in deeper burns.
2. **Proliferation of granulation tissue:** This is a normal physiological response to injury, where new tissue forms to replace the damaged tissue. In burns, granulation tissue formation is accelerated due to the release of growth factors and cytokines.
3. **Altered skin sensation:** Burns can damage nerves, leading to changes in skin sensation, such as hypo- or hyperalgesia, depending on the extent of nerve damage.
4. **Absence of epidermis and dermal papilla:** In deep second-degree burns, the epidermis and dermal papilla are destroyed, leading to the absence of these structures.

**Why Each Wrong Option is Incorrect:**
A. **Burned skin:** This option is incorrect because it does not address any specific feature of deep second-degree burns. Burns are classified based on the depth of the injury, not the appearance of the affected skin.
B. **Hypersensitivity:** This option is incorrect because it does not specifically relate to deep second-degree burns. Hypersensitivity is a broad concept and does not address the detailed features of the burn injury.
C. **Lack of blisters:** While it is true that deep second-degree burns may not always produce blisters, the correct answer addresses the presence of blisters in burns, which is a key feature of deep second-degree burns.
D. **Granulation tissue formation:** Although granulation tissue formation is present in burns, option D does not address the specific features of deep second-degree burns. The correct answer focuses on the presence of altered skin sensation, which is a key feature of deep second-degree burns.

**Clinical Pearl:**
Deep second-degree burns are characterized by the presence of blisters, altered skin sensation, and absence of epidermis and dermal papilla. These features allow for a proper understanding of the severity and depth of the burn injury.