**Core Concept**
Scurvy is a disease caused by a deficiency of vitamin C (ascorbic acid) in the diet, leading to impaired collagen synthesis and connective tissue damage. It affects multiple systems, including the skin, bones, and blood vessels.

**Why the Correct Answer is Right**
The correct answer is related to the pathophysiology of scurvy, which primarily involves the inhibition of collagen synthesis due to a lack of vitamin C. Vitamin C is necessary for the hydroxylation of proline and lysine residues in collagen, a process catalyzed by the enzyme prolyl hydroxylase. Without adequate vitamin C, this process is impaired, leading to the accumulation of unhydroxylated collagen and the characteristic symptoms of scurvy.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because scurvy does indeed cause fatigue and weakness, which are symptoms of the disease.
**Option B:** This option is incorrect because scurvy does indeed cause skin lesions and poor wound healing, which are direct consequences of impaired collagen synthesis.
**Option C:** This option is incorrect because scurvy does indeed cause joint pain and swelling, which are symptoms of the disease.

**Clinical Pearl / High-Yield Fact**
One of the key features of scurvy is that it can be prevented and treated with vitamin C supplementation. In fact, the British Royal Navy used to give sailors a daily ration of citrus fruits, which are rich in vitamin C, to prevent scurvy during long voyages.

**Correct Answer:** D.