Scabies oral drug of choice:
Correct Answer: Ivermectin
Description: Ref: Katzung, 14th ed. pg. 939, 1075; KDT, 6th ed. pg. 864* Scabies is caused by an ectoparasite sarcoptes scabei. It is highly contagious. The mite burrows through the epidermis, laying eggs which form papules that itch intensely.* Most common site of entry- finger webs.* Drugs used are:# Permethrin 5%: broad spectrum and potent insecticide, currently most efficacious.* It is DOC for scabies.* MOA: It causes neurological paralysis in insects by delaying depolarization.* Single application needed in most cases.* Very less toxicity; 100% cure rate.# Lindane: another broad spectrum insecticide.Efficacy lower than permethrin.MOA: kills lice and mites by penetrating through their chitinous cover and affecting the nervous system.# Benzyl benzoate: Oily liquid with a faint aromatic smell.It is applied over face and neck after a bath. A second coat is applied next day which is washed after 24 hours.# Crotamiton# Sulfur# Ivermectin: Highly effective in scabies and pediculosis as well. Oral DOC in scabies.* It is the only ORALLY administered drug which is used for scabies (ectoparasitosis)* A single dose of 0.2mg/kg has cured almost 90-100% of population.* It is contraindicated in children <5 yrs, pregnant and lactating women.
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now