**Question:** Satellite lesions in eye is caused by –

A. Viral infection
B. Bacterial infection
C. Fungal infection
D. Tuberculosis

**Core Concept:** Satellite lesions are a clinical feature observed in ocular tuberculosis (TB) infection, where multiple, scattered, and non-palpable lesions are seen around the primary, palpable primary lesion (mainly in the choroid or retina). These lesions are caused by the hematogenous spread of Mycobacterium tuberculosis from the primary focus to the ocular tissues.

**Why the Correct Answer is Right:** The correct answer is D. Tuberculosis (TB), as it is a common infectious disease caused by Mycobacterium tuberculosis, which can spread hematogenously (bloodstream) to various organs, including the eye. In ocular TB, satellite lesions are indicative of the systemic involvement and can be observed in the choroid or retina.

**Why Each Wrong Option is Incorrect:**

A. Viral infections, like herpes simplex virus (HSV) and varicella-zoster virus (VZV), typically present with primary ocular lesions (herpetic keratitis and uveitis) but not satellite lesions.

B. Bacterial infections like Staphylococcus aureus and Streptococcus pyogenes predominantly cause localized infections of the cornea or conjunctiva without satellite lesions.

C. Fungal infections, such as those caused by Candida or Aspergillus species, typically present with diffuse ocular involvement and not satellite lesions.

**Clinical Pearl:** A thorough understanding of the clinical features of different ocular infections is essential for accurate diagnosis and appropriate management. Satellite lesions in the eye should raise suspicion for ocular tuberculosis, prompting further investigations like TB serology, Mantoux test, or PCR test to confirm the diagnosis. Early diagnosis and treatment of ocular TB are crucial to prevent severe vision loss and other complications.