**Question:** Satellite lesions in eye is caused by

A. Herpes simplex virus (HSV)
B. Varicella-zoster virus (VZV)
C. Human papillomavirus (HPV)
D. Cytomegalovirus (CMV)

**Core Concept:** Satellite lesions are a clinical manifestation of an ocular infection, where a primary focus (primary lesion) exists, and secondary lesions (satellite lesions) appear around it. These lesions are typically seen in viral infections involving the eye.

**Why the Correct Answer is Right:** The correct answer is caused by Varicella-zoster virus (VZV), which is responsible for chickenpox (varicella) and shingles (herpes zoster). When the virus reactivates, it can lead to ocular involvement, including satellite lesions.

**Why Each Wrong Option is Incorrect:**

A. Herpes simplex virus (HSV) primarily causes herpes labialis (cold sores) and herpes genitalis and is not typically associated with satellite lesions in the eye.
B. Human papillomavirus (HPV) causes warts and is not typically associated with ocular involvement.
C. Cytomegalovirus (CMV) is primarily associated with immunocompromised patients and can cause retinitis, while satellite lesions are not a typical manifestation.

**Why the Correct Answer is Right:**

VZV can cause ocular involvement due to its ability to produce multiple lesions in the ocular structures, including cornea, conjunctiva, and episclera. Satellite lesions are secondary to the primary ocular infection and appear as a result of the spread of the virus from the primary focus.

**Clinical Pearl:** While satellite lesions are not a common manifestation in ocular herpes simplex virus (HSV) infection, primary ocular VZV infection can present with satellite lesions. Early diagnosis and treatment are crucial for preventing severe complications like keratitis or retinitis.