**Core Concept:** Salbutamol is a short-acting beta-2 agonist used for the relief of bronchospasm in asthma and other respiratory disorders. It acts by stimulating beta-2 receptors, leading to relaxation of smooth muscles in the airways and bronchioles, and increased secretion of mucus.

**Why the Correct Answer is Right:** Salbutamol's common side effects are dose-related, meaning they increase when the drug dose is higher. The correct answer indicates that the most common dose-related side effects occur at higher doses.

**Why Each Wrong Option is Incorrect:**

A. **Incorrect because salbutamol is a relatively safe drug. Side effects are dose-related, not dose-independent.**
B. **Incorrect because the question asks for the most common side effects, not the least.**
C. **Incorrect because this option refers to a less common side effect, not the most common.**
D. **Incorrect as it does not match the focus of the question, which is about dose-related side effects.**

**Clinical Pearl / High-Yield Fact:** Understanding the relationship between salbutamol dose and side effects is essential for safe prescribing and patient care. Adequate bronchodilation is crucial in asthma management, but overdosing can lead to detrimental effects.

**Correct Answer:** .