Sago spleen is seen in –
Correct Answer: Amyloidosis
Description: Appearance of Spleen with deposits of Amyloid in the stroma of the red pulp is known as lardaceous spleen and within the stroma of the white pulp is known as sago spleen.
Spleen involvement in Amyloidosis
↓ ↓
Sago Spleen Lardaeeous Spleen
Splenomegaly is not marked Splenomegaly Marked (Moderate to large spleen)
Cut surface lookalike it is impregnated with cranes Cut surface shows a diffuse large map like the area of pale waxy translucency and hence called Lardaeeous (Lard like; Fatty)
of sand (nodules resembling tapioca-like granules) Deposits of Amyloid in Red pulp (Connective tissue and splenic sinus spare the follicles
i.e. sago grains and hence called Sago's spleen.
Deposition of amyloid in the while pulp walls of
the arterioles replace the follilcle
Category:
Pathology
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