Sacrococcygeal teratoma, marker is –
**Core Concept**
Sacrococcygeal teratoma (SCT) is a type of congenital tumor that arises from the sacrococcygeal region, typically presenting at birth. SCTs are often associated with elevated levels of specific tumor markers, which aid in diagnosis and management.
**Why the Correct Answer is Right**
The primary marker associated with sacrococcygeal teratoma is Alpha-fetoprotein (AFP). Elevated levels of AFP are found in the majority of SCT cases, making it a valuable diagnostic tool. AFP is a protein produced by the yolk sac and fetal liver during embryonic development, and its levels are typically high in germ cell tumors, including SCTs.
**Why Each Wrong Option is Incorrect**
**Option A:** Beta-human chorionic gonadotropin (β-hCG) is a marker associated with choriocarcinoma and other germ cell tumors, but not specifically with SCT.
**Option B:** Lactate dehydrogenase (LDH) is a non-specific marker that can be elevated in various types of tumors, but it is not a specific marker for SCT.
**Option C:** Carcinoembryonic antigen (CEA) is a marker associated with colorectal cancer and other malignancies, but not specifically with SCT.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that elevated AFP levels in newborns can also be indicative of other conditions, such as neural tube defects or abdominal wall defects, highlighting the need for a comprehensive diagnostic approach.
**Correct Answer: A. Alpha-fetoprotein (AFP)**