Rubella virus was isolated in-
**Core Concept**
The **rubella virus** is a member of the Togaviridae family and is the causative agent of **German measles**. Isolation of the virus is crucial for understanding its pathogenesis and development of diagnostic tests. The **rubella virus** was first isolated in cell culture.
**Why the Correct Answer is Right**
The correct answer is related to the historical context of **rubella virus** isolation. The **rubella virus** was first isolated in 1962 by **Parkman** and **Buescher**. This isolation was a significant milestone in the study of **rubella** and paved the way for the development of vaccines.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not correspond to the correct historical context of **rubella virus** isolation.
**Option B:** This option is also incorrect as it is not related to the **rubella virus** isolation.
**Option C:** This option is incorrect because it does not match the correct year and context of **rubella virus** isolation.
**Clinical Pearl / High-Yield Fact**
The **rubella virus** isolation led to the development of a vaccine, which has been instrumental in preventing **congenital rubella syndrome**. Vaccination against **rubella** is a crucial public health measure.
**Correct Answer:** D. 1962 by Parkman and Buescher