Medical MCQ-Roopa Devi, a 65-year-old female with ovarian cancer is being treated with cisplatin-based chemotherapy. All of the following are used to limit the toxicityof cisplatin except:

Roopa Devi, a 65-year-old female with ovarian cancer is being treated with cisplatin-based chemotherapy. All of the following are used to limit the toxicityof cisplatin except:

N-acetylcysteine

Slow rate of infusion

Chloride diuresis

Amifostine

Question Category:

Pharmacology

Correct Answer:

N-acetylcysteine

Description:

(Ref: Harrison 18th/697) N-acetylcysteine is used for paracetamol poisoining whereas slow intravenous infusion and chloride dieresis along with amifostine can limit cisplatin induced nephrotoxicity.

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