**Core Concept**
RNA primers are short RNA molecules essential for initiating DNA replication and repair. They are synthesized by RNA primase, an enzyme that catalyzes the formation of RNA-DNA hybrids.
**Why the Correct Answer is Right**
RNA primase is a DNA-dependent RNA polymerase that synthesizes RNA primers on the template strand of DNA. It recognizes specific sequences on the DNA template and initiates RNA synthesis, creating a short RNA-DNA hybrid. This process is crucial for the initiation of DNA replication and repair, as it provides a free 3'-hydroxyl group for the subsequent addition of nucleotides by DNA polymerase. RNA primase is a key enzyme in the replication process, and its activity is essential for the synthesis of RNA primers.
**Why Each Wrong Option is Incorrect**
**Option A:** Incorrect because RNA primase is a DNA-dependent RNA polymerase, not a DNA-dependent DNA polymerase.
**Option B:** Incorrect because DNA polymerase is responsible for elongating the RNA primer, not synthesizing it.
**Option C:** Incorrect because the correct enzyme responsible for synthesizing RNA primers is RNA primase, not DNA primase.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that RNA primers are synthesized by RNA primase, which recognizes specific sequences on the DNA template to initiate RNA synthesis. This process is crucial for the initiation of DNA replication and repair.
**Correct Answer:** C. RNA primase.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.