Rivastigmine and Donepezil are drugs used predominantly in the management of which of the following conditions?
Correct Answer: Dementia
Description: In Alzheimer's disease the most common cause of dementia, there is a reduction in the activity of acetylcholine within the brain due to loss of cholinergic activity within the brain due to loss of cholinergic neurons in the nucleus basalis of Meyne . Both Rivastigmine and Donepezil are cholinesterase inhibitors used in the management of dementia. These drugs reduce the degeneration of acetylcholine by inhibiting the enzyme Acetyl cholinesterase.Ref: Alzheimer's Disease And Dementia in Down Syndrome And Intellectual Disabilities By Vee P. Prasher page 85.
Category:
Psychiatry
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