Risk of the damage of fetus by maternal rubella is maximum if mother gets infected in
Correct Answer: 6-12 weeks of pregnancy
Description: Congenital Rubella Syndrome (CRS):
CRS is said to have occurred if:
– Infant has IgM rubella antibodies shortly after birth, or
– IgG antibodies persist for more than 6 months
Major determinant of extent of fetal infection in CRS: Gestational age at which fetal transmission occurs,
– Infection in I trimester: MOST DISASTROUS TIME
1. Abortions
2. Still births
3. Skin lesions: blueberry muffin lesions
4. ‘Triad of Congenital Rubella Syndrome’
i. Sensorineural deafness
ii. Congenital heart defects (MC is PDA)
iii. Cataracts
– Infection in early part of II Trimester: Deafness (only)
– Infection after 16 weeks POG: No major abnormalities
Risk of fetal damage in CRS:
Category:
Social & Preventive Medicine
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