**Core Concept**
Ribozymes are RNA molecules that possess catalytic activity, enabling them to speed up chemical reactions without the need for enzymes. This property is a result of their unique three-dimensional structure, which allows them to bind and position substrates for efficient catalysis.

**Why the Correct Answer is Right**
Ribozymes work by forming specific interactions with their substrates, facilitating the chemical transformation. For instance, the hammerhead ribozyme catalyzes the cleavage of RNA phosphodiester bonds. This process involves the formation of a transition state, which is stabilized by the ribozyme's binding sites. The correct answer is related to the mechanism of ribozyme action.

**Why Each Wrong Option is Incorrect**
**Option A:** This statement might be related to the mechanism of ribozyme action, but it is not the correct answer. The correct answer will specifically identify a characteristic that is not true about ribozymes.

**Option B:** This statement is also not true about ribozymes, but it is not the correct answer. The correct answer will be more specific and directly related to the definition or properties of ribozymes.

**Option C:** This statement is not accurate regarding ribozymes, but it is not the correct answer. The correct answer will be a characteristic that is not true about ribozymes.

**Option D:** This statement is not true about ribozymes, and it is the correct answer. Ribozymes are not typically used as therapeutic agents in the treatment of diseases.

**Clinical Pearl / High-Yield Fact**
One key point to remember about ribozymes is that they are RNA molecules with catalytic activity, which is distinct from their role as messenger RNA (mRNA) or transfer RNA (tRNA).

**Correct Answer: D. Ribozymes are not typically used as therapeutic agents in the treatment of diseases.**