Rheumatoid factor is directed against ?
Correct Answer: IgG
Description: Ans. is 'a' i.e., IgG Rheumatoid factor in Rheumatoid Ahritis is an IgM antibody directed against the Fc fragment of IgG. Rheumatoid factor in Rheumatoid Ahritis is an IgM antibody directed against the Fe fragment of IgG. Anti CCP antibodies are most specific blood test for rheumatoid ahritis (specificity - 95%). Rheumatoid factor is positive in only 10% of patients with JRA.
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Pathology
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