Reversed splitting of S2 heart sound is heard in
**Core Concept**
Reversed splitting of the second heart sound (S2) is a phenomenon where the aortic component (A2) of the S2 sound is delayed, causing the pulmonary component (P2) to precede it. This occurs due to alterations in the timing of ventricular ejection and/or the presence of conditions affecting the aortic valve or the ventricular septum.
**Why the Correct Answer is Right**
Reversed splitting of the S2 sound is typically associated with conditions that delay the aortic valve closure, such as aortic regurgitation or conditions affecting the left ventricular outflow tract. In aortic regurgitation, the regurgitant flow from the aorta into the left ventricle delays the closure of the aortic valve, causing the A2 sound to be delayed. This results in the P2 sound preceding the A2 sound, producing the characteristic reversed splitting of the S2 sound.
**Why Each Wrong Option is Incorrect**
**Option A:**
This option is incorrect because conditions affecting the pulmonary valve or pulmonary artery, such as pulmonary stenosis or pulmonary hypertension, typically cause an accentuated P2 sound, not reversed splitting.
**Option B:**
This option is incorrect because left bundle branch block (LBBB) typically causes a wide QRS complex on the electrocardiogram and can cause a "paradoxical" or "wide" splitting of the S2 sound, but not reversed splitting.
**Option C:**
This option is incorrect because conditions affecting the right ventricular outflow tract, such as pulmonary stenosis, typically cause an accentuated P2 sound, not reversed splitting.
**Clinical Pearl / High-Yield Fact**
Reversed splitting of the S2 sound is often associated with aortic regurgitation, a condition where the aortic valve fails to close properly, allowing blood to flow back into the left ventricle.
**Correct Answer: C.** Pulmonary hypertension.