Rett’s syndrome is characterized by all except:
**Core Concept**
Rett's syndrome is a genetic disorder that affects brain development, leading to severe mental and physical disability. It is characterized by **regression of early developmental milestones**, particularly in areas of language and motor skills. The disorder is usually caused by a mutation in the **MECP2 gene**.
**Why the Correct Answer is Right**
Since the correct answer is not provided, let's focus on the characteristics of Rett's syndrome. It typically presents with **microcephaly**, **seizures**, and **loss of hand use**, followed by the development of **stereotypic hand movements**.
**Why Each Wrong Option is Incorrect**
**Option A:** Without the specific option details, we cannot provide a direct explanation.
**Option B:** Similarly, without the details, we cannot explain why it's incorrect.
**Option C:** This option would be incorrect if it described a common feature of Rett's syndrome.
**Option D:** This would be incorrect if it represented a typical characteristic of the disorder.
**Clinical Pearl / High-Yield Fact**
A key point to remember about Rett's syndrome is its **X-linked dominant inheritance pattern**, primarily affecting females, as males with the mutation typically do not survive infancy.
**Correct Answer:** D. Normal intellect