**Core Concept**
Retinoblastoma is a malignant tumor of the retina, primarily affecting children under the age of 5. It is a type of cancer that arises from the immature cells of the retina, which are responsible for converting light into electrical signals for vision. The disease often presents with leukocoria (white reflex), strabismus, or glaucoma.

**Why the Correct Answer is Right**
Retinoblastoma is characterized by mutations in the RB1 gene, a tumor suppressor gene that regulates cell growth and division. The disease can be hereditary, with a family history of retinoblastoma, or sporadic, with no known genetic predisposition. Treatment options for retinoblastoma include chemotherapy, radiation therapy, laser photocoagulation, and enucleation (surgical removal of the affected eye).

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because retinoblastoma is not typically associated with a viral etiology.
**Option B:** This option is incorrect because retinal detachment is a complication of retinoblastoma, but it is not a primary characteristic of the disease.
**Option C:** This option is incorrect because glaucoma is a potential complication of retinoblastoma, but it is not a defining feature of the disease.

**Clinical Pearl / High-Yield Fact**
Retinoblastoma is the most common primary intraocular malignancy in children, accounting for approximately 3% of all childhood cancers. Early detection and treatment are critical for improving prognosis and reducing the risk of metastasis.

**Correct Answer:** Not Provided.