**Core Concept**
The treatment of uniocular retinoblastoma depends on the stage of the disease, with early stages often manageable with less invasive methods to preserve vision and the eye. **Retinoblastoma** is a malignant tumor of the retina, and its treatment aims to cure the disease while preserving as much vision and ocular function as possible. The staging of retinoblastoma is crucial for determining the appropriate treatment approach.

**Why the Correct Answer is Right**
Given that the question is incomplete regarding the specific treatment options provided for each choice, the general approach for treating uniocular retinoblastoma in the 1st and 2nd stages typically involves **chemotherapy**, **laser photocoagulation**, **cryotherapy**, or **brachytherapy**, depending on the tumor's size and location. These methods are preferred over enucleation (surgical removal of the eye) when possible, to preserve the eye and its function.

**Why Each Wrong Option is Incorrect**
**Option A:** Without the specific details of option A, it's challenging to provide a direct explanation for its incorrectness.
**Option B:** Similarly, without knowing what option B entails, we cannot directly address why it might be incorrect.
**Option C:** And option C's incorrectness would depend on its specifics, which are not provided.
**Option D:** The same issue applies to option D, as the question lacks the necessary details to evaluate these choices properly.

**Clinical Pearl / High-Yield Fact**
A critical point in treating retinoblastoma is the preservation of vision and the eye whenever possible, especially in early stages. The treatment choice depends heavily on the tumor's size, location, and the presence of any extraocular extension or metastasis.

**Correct Answer:** Correct Answer: B. Local treatment (laser/ cryotherapy) + Chemotherapy