Which of the following is responsible for protection from ultraviolet rays: September 2011
**Core Concept**
Melanocytes are responsible for producing melanin, the pigment that protects the skin from ultraviolet (UV) radiation. This is achieved through the process of melanin synthesis, where melanocytes convert the amino acid tyrosine into melanin. The resulting melanin is then transferred to adjacent keratinocytes, providing protection against UV-induced damage.
**Why the Correct Answer is Right**
Melanocytes contain the enzyme tyrosinase, which catalyzes the conversion of tyrosine into melanin. This process involves a series of enzyme-catalyzed reactions, resulting in the production of eumelanin and pheomelanin, which are the two main types of melanin responsible for skin pigmentation. The melanin produced by melanocytes serves as a natural sunscreen, absorbing UV radiation and preventing damage to the skin's DNA and cellular structures. This is particularly important in protecting against UV-induced skin cancer and photoaging.
**Why Each Wrong Option is Incorrect**
**Option A:** The stratum corneum is the outermost layer of the skin, composed of dead keratinocytes that provide a physical barrier against external factors, including UV radiation. However, it does not produce melanin or provide direct protection against UV rays.
**Option B:** Langerhans cells are a type of immune cell found in the skin, involved in the presentation of antigens to T-cells. They do not produce melanin or play a direct role in protecting the skin from UV radiation.
**Option C:** Apocrine sweat glands are responsible for producing a type of sweat that is rich in protein and lipids. This sweat helps to regulate body temperature and has antimicrobial properties, but it does not provide protection against UV radiation.
**Clinical Pearl / High-Yield Fact**
Melanocytes are responsible for producing melanin in response to UV radiation, but they can also be stimulated by other factors, such as hormonal changes and genetic mutations. This is why individuals with fair skin or a history of UV-induced skin cancer are often advised to use sunscreen and protective clothing to prevent further damage.
β Correct Answer: D. Melanocyte