Resistance to zidovirdine develops due to:

A. Mutation at reverse transcriptase

B. Increased efflux of the drug from inside the cell

C. Increased metabolism of the drug

D. Decreased zidovudine triphosphate formation

Correct Answer: Mutation at reverse transcriptase

Description: "Resistance to AZT (Zidovudine) occurs by point mutations which alter the reverse transcriptase enzyme,"

Category: Pharmacology

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