Regarding the lipid or liposomal formulation of amphotericin B which of the following statements is accurate

A. They are expensive to use than conventional amphotericin B

B. There are more effective in fungal infections than conventional preparations because they increase tissue uptake of amphotericin B

C. They may decrease the niprotoxicity of amphotericin B

D. They have wider spectrum of antifungal activity than conventional formulation of amphotericin B

Correct Answer: They may decrease the niprotoxicity of amphotericin B

Description: Ref-KDT 6/e p758 Newer liposomal preparations of amphotericin B have the following features: Less chances of nephrotoxicity and infusion related reactions Lesser uptake in the tissues like kidney More expensive Similar in efficacy and antifungal spectrum as conventional preparations

Category: Anatomy

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