Regarding scoline apnoea all are true except
Correct Answer: Deficiency of cholinesterase
Description: C i.e. Deficiency of cholinesterase Scoline apnoea is prolonged residual paraysis after administration of succinyl choline (suxamethonium) 1/t apnoea. It can be seen in patients with hereditary (inherited) atypical pseudochdinesterase enzyme (homozygous >>> heterozygous)Q and phase II (non depolerizing) blockQ. Decreased level of normal pseudocholinestrerase (not choline esterase) enzymeQ would usually not result in prolonged apnea unless the surgery was very sho. In other words, in contrast to doubling or tripling of blockade duration seen in patients with heterozygous atypical enzyme or patients with low (normal/typical) enzyme levels, patients with homozygous atypical enzyme will have a very prolonged blockade (4-8 hrs) following Sch administration. Prolonged paralysis (apnoea) should be treated with continued mechanical ventilation until muscle function returns to normal which has reduced moality to very low levelsQ.
Category:
Anaesthesia
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now