Pathology Regarding oncogenesis: All are true except: A Topoisomerase II causes breaks in strands B p53 is the most common oncogene mutation causing malignancy in humans C At G2-M phase there is loss of inhibitors controlling cell-cycle D Decrease in telomerase activity causes anti-tumor effects 💡 Explanation Regarding oncogenesis: All are true except: ✓ Correct Answer: B. p53 is the most common oncogene mutation causing malignancy in humans