Gynaecology & Obstetrics Regarding adenocarcinoma in situ, all are true, except: A Invasive cancer cannot be ruled out without diagnostic excisional procedures B Hysterectomy is preferred for women who have completed childbearing C Frequently extends into the endocervical canal D Negative margins on excised specimen ensures complete resection of the disease. 💡 Explanation Regarding adenocarcinoma in situ, all are true, except: ✓ Correct Answer: D. Negative margins on excised specimen ensures complete resection of the disease.