**Core Concept**
Aldose reductase inhibitors are a class of drugs that target the enzyme aldose reductase, which is involved in the polyol pathway of glucose metabolism. This pathway is activated in hyperglycemic conditions, such as diabetes mellitus, leading to the accumulation of sorbitol in cells and subsequent cellular damage.

**Why the Correct Answer is Right**
Aldose reductase inhibitors work by competitively inhibiting the action of aldose reductase, thereby reducing the conversion of glucose to sorbitol. This decrease in sorbitol production helps to alleviate the secondary complications of diabetes, such as diabetic retinopathy, neuropathy, and nephropathy. The correct answer is related to the use of aldose reductase inhibitors in the management of these complications.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because aldose reductase inhibitors are not primarily used for the treatment of hyperglycemia itself, but rather for the prevention of secondary complications.
**Option B:** This option is incorrect because while aldose reductase inhibitors may have some beneficial effects on blood glucose levels, their primary mechanism of action is not through the regulation of blood glucose.
**Option C:** This option is incorrect because aldose reductase inhibitors are not used for the treatment of hypertension.

**Clinical Pearl / High-Yield Fact**
Aldose reductase inhibitors, such as epalrestat, are most effective in preventing the progression of diabetic neuropathy when used in conjunction with tight glycemic control.

**Correct Answer:** D.