**Core Concept**
The management of chronic low back pain involves a multidisciplinary approach, including pharmacological, physical, and behavioral interventions. The goal is to improve function and reduce pain, while minimizing the risk of adverse effects and medication overuse.

**Why the Correct Answer is Right**
Chronic low back pain is often managed with a combination of medications, including nonsteroidal anti-inflammatory drugs (NSAIDs), muscle relaxants, and opioids. However, the use of opioids in chronic low back pain is not recommended due to the risk of addiction, tolerance, and overdose. Furthermore, long-term opioid use can lead to hyperalgesia, a condition characterized by increased sensitivity to pain.

**Why Each Wrong Option is Incorrect**
**Option A:** This option may be incorrect, as the specific medication is not mentioned.
**Option B:** This option may be incorrect, as the specific medication is not mentioned.
**Option C:** This option may be incorrect, as the specific medication is not mentioned.

**Clinical Pearl / High-Yield Fact**
The American College of Physicians recommends nonpharmacological interventions, such as exercise, cognitive-behavioral therapy, and education, as the first-line treatment for chronic low back pain. These interventions have been shown to be effective in reducing pain and improving function.

**Correct Answer:** D.