Recommended step in salicylate toxicity is: September 2006
**Core Concept**
Salicylate toxicity, also known as aspirin toxicity, occurs when the body takes in excessive amounts of salicylates, which can lead to a range of systemic complications. The management of salicylate toxicity involves a multidisciplinary approach, including supportive care and specific interventions to counteract the toxic effects.
**Why the Correct Answer is Right**
The recommended step in managing salicylate toxicity is to administer activated charcoal, which helps to prevent the absorption of additional salicylates from the gastrointestinal tract. This is typically done within 1 hour of ingestion and is most effective when done early. Activated charcoal works by adsorbing the salicylates, thereby reducing their absorption and potentially mitigating the severity of the toxicity.
**Why Each Wrong Option is Incorrect**
**Option A:** Gastric lavage is not recommended as an initial step in managing salicylate toxicity, as it may cause more harm than good, particularly if done after a significant amount of time has passed since ingestion.
**Option B:** Hemodialysis may be considered in severe cases of salicylate toxicity, but it is not the initial step in management.
**Option C:** Forced diuresis is not an effective method for removing salicylates from the body.
**Clinical Pearl / High-Yield Fact**
Activated charcoal is most effective when administered within 1 hour of ingestion and should be considered as part of the initial management of salicylate toxicity.
**Correct Answer: A. Activated charcoal.**