Raynaud Braude phenomenon is seen in
Correct Answer: Candida albicans
Description: Candida species:General characteristicsCultural characteristics*Gram positive ovoid, elongated budding yeast-like fungi*Major pathogenic species: C.albicans, C.tropicalis, C.glabrata, C.parapsilosis, C.krusei*Non capsulated*Candida is a human commensal so infection is mostly endogenous*Impoant Oppounistic pathogen*Blood agar and SDA - creamy white, some are pasty and few are rough colonies*Preferred media - Sabouraud dextrose agar with or without antibiotics (Gentamicin, chloramphenicol and cycloheximide) Virulence factorsClinical features*Adhesins*Urease activity*Extracellular proteinases*Phospholipases*Lipases*Hydrolytic enzymes*Phenotypic switching: from budding yeasts- Pseodohyphae-true hyphae*Superficial infections: Cutaneous (interigo, diaper rash), nail (paronychia and onychomycosis) and mucosal infections (oral thrush, stomatitis and vaginal candidiasis)*Deep infections (esophagitis, GIT candidiasis, endocarditis, UTIs, Meningitis, Ocular candidiasis)*Disseminated candidiasis and candidaemiaDiagnosisTreatment*Microscopy: Direct Gram stain and KOH mount, Calcofluor white stain and LPCB*Culture: Blood agar and SDA*Germ tube test: Reynauds-Braud phenomenon positive*Corn meal agar with Tween 80: identification of species*CHROM agar inoculation: different colour by Candida species*Sugar fermentation and assimilation test*DOC - Amphotericin B*Alternative - Echinocandins and Azoles (Ref: Ananthanarayan 9th edition, p611-612)
Category:
Microbiology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now