Radioprotective drug(s) is/are :
Correct Answer: Amifostine
Description: Ans: A (Amifostine) Radio Protective DrugsAmifostine (VVR 2721} has free SH group which scavenge the free radicals produced due to radio therapy.Free radical scavenger agents such as sulphydryl - containing compounds tend to make cells more resistant. They have also been shown to reduce chromosome abnormalities associated with radiation. This suggests a potential use in reducing treatment induced cancers. The thiol containing drug amifostine (WR 2721) is the best studied drug of this type. Randomized trial has shown that amifostine reduce treatment related toxicities, including radiation induced parotid damage (xerostmia) & dsplatin induced nephrotoxicity' - Devita 7th/ 275Also used for reducing S/E of radiomimeticdrug (dsplatin)Antiradiation agent for astonanats.Radioprotective agents are -* Amifostine (WR 2721)* IL-1* Zinc Oxide* GM-CSF* Pentoxyphyiline* Etramustine* Chlorhexidine* KI* Melatonin* Antioxidant (vit C, E, A)Factors | RadiosensitivityHypoxic environmentSlow or no divisionS-phase of cell cycleRadiation protectors (Amifostine)Chemotherapeutic agents are radiosensitizer not radioprotecter
Category:
Radiology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now