String sign is a radiological feature of –
**Core Concept**
The string sign is a radiological feature that describes the narrowing of the terminal ileum due to fibrosis and contraction, often seen in diseases that cause chronic inflammation and scarring in the ileocecal region.
**Why the Correct Answer is Right**
Ileocecal tuberculosis is a form of extrapulmonary tuberculosis that affects the ileocecal region. The chronic inflammation and scarring caused by tuberculosis lead to fibrosis and contraction of the ileocecal region, resulting in the characteristic string sign on imaging. The string sign is a result of the narrowing of the terminal ileum, making it a key radiological feature of ileocecal tuberculosis.
**Why Each Wrong Option is Incorrect**
**Option A:** Crohn's disease can cause narrowing of the terminal ileum, but it is not typically associated with the string sign. Crohn's disease tends to cause more extensive and diffuse inflammation, leading to a cobblestone appearance on imaging.
**Option B:** Ulcerative colitis typically affects the colon and is not commonly associated with the string sign. Ulcerative colitis causes diffuse inflammation of the colon, leading to a loss of haustral folds and a lead pipe appearance on imaging.
**Option D:** Ischemic colitis can cause narrowing of the colon, but it is not typically associated with the string sign. Ischemic colitis is a result of impaired blood flow to the colon, leading to necrosis and potentially perforation.
**Clinical Pearl / High-Yield Fact**
The string sign is a classic radiological feature of ileocecal tuberculosis, but it is not pathognomonic. A high index of suspicion is necessary to diagnose ileocecal tuberculosis based on imaging findings alone.
**β Correct Answer: C. Ileocecal tuberculosis**